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Clinical Trials
BrainPOP delivers perioperative clinical trials that generate direct biological evidence of how treatments reach and affect brain tumours. The portfolio includes investigator-initiated and industry-supported studies.
Select a trial to learn more about eligibility, participation and study details.
Recruiting
PRIME
Recurrent glioblastoma
A clinical trial testing a new targeted treatment (BMS-986504) in people with glioblastoma that has returned. Uses a perioperative approach to study how the drug reaches the tumour and what effect it has.
· Interventional
· Perioperative
· Phase 0/2
BrainPOP Precision
Multiple tumour types
A tumour molecular profiling study that analyses tumour, blood and imaging data to better understand each person’s brain cancer and guide treatment decisions. Supports matching patients to clinical trials and improving care over time.
· Precision medicine
· Translational
· Non-interventional
GIANT
Newly diagnosed glioblastoma
A clinical trial testing two immunotherapy drugs, nivolumab and relatlimab, in people with newly diagnosed glioblastoma. Uses a perioperative approach to study how the drug reaches the tumour and what effect it has.
· Interventional
· Perioperative
· Phase 2
Closed
AnHEART
IDH-mutant glioma
A clinical trial testing safusidenib in people with IDH-mutant glioma, studying safety and how the drug affects the tumour when given before surgery. Uses a perioperative approach to understand how the drug behaves in the body and tumour.
· Interventional
· Perioperative
· Phase 0/2
PRISM
Brain metastases
A clinical trial studying the timing of surgery after stereotactic radiosurgery (focused radiation) for brain metastases. Aims to understand how treatment timing affects tumour response and the body’s immune response.
· Interventional
· Translational
· Radiotherapy
Are you a patient or carer looking for a trial?
Clinical trial options vary depending on your diagnosis and treatment plan. Speak with your treating specialist about whether a trial may be suitable for you.
For a national list of brain cancer clinical trials in Australia, visit anzctr.org.au or clinicaltrials.gov.